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Cusabio.jpg

艾美捷科技特约代理CUSABIO公司产品。Cusabio专注于研发生产基因、蛋白、抗体、ELISA试剂盒、体外诊断原料、小分子等产品,还涉及食品安全和药物残留领域。

 

CUSABIO is a National High-Tech Enterprise with research, production and sales in one. After 11 years of effort, CUSABIO has become a good partner to researchers through worldwide. We are dedicated to providing 60,000+ validated antibodies, 6000+ recombinant proteins, 580+ cytokines and thousands of ELISA kits to global customers in the research fields of cancer, cell biology, immunology, neuroscience, epigenetics, etc. All kinds of our products can meet customers' different demands in various scientific research fields.

 

Cusabio的主要产品包括:

(1)Kit

ELISA Kit

Elisa Kit For Food Safety & Drug Residues

Hot Product

Food Safety Small Molecule Antigen

(2)Protein

Native Protein

Recombinant Protein

Active Protein

Transmembrane Protein

(3)Antibody

Polyclonal Antibodies

Secondary Antibodies

Monoclonal Antibodies

Tag/Control Antibodies

Small Molecules Antibodies

ChIP Antibodies

Antibody Pairs

Recombinant Antibodies

Custom Antibodies

(4)Molecular Biology Product

RT-PCR Primers

Clone

Tools Enzyme

Other Small Molecule Antigen

Peptide

(5)Wisherkon Food Safety Test Kits

ELISA Test Kits

Rapid Test Card/Strip

Chemical Reagents

(6)Raw Material For IVD Kit

CUSAg

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Lonza Logo.jpg

艾美捷科技有限公司代理Lonza的生命科学相关产品,包括:


  (1)Primary and Stem Cells - 原代及干细胞

(http://www.amyjet.com/Index/lists/catid/27/kid/19/p/48.html)

  (2)Transfection - 转染系列产品

(http://www.amyjet.com/Index/lists/catid/27/kid/19/p/39.html)

  (3)Endotoxin Detection - 内毒素检测相关产品

(http://www.amyjet.com/Index/lists/catid/27/kid/19/p/33.html)

  (4)Electrophoresis - 电泳相关产品 

(http://www.amyjet.com/Index/lists/catid/27/kid/19/p/25.html)

  (5)Culture Medium and Reagents - 细胞培养基及相关试剂

(http://www.amyjet.com/Index/lists/catid/27/kid/19/p/5.html)

  (6)Cell Analysis - 细胞分析相关产品 

(http://www.amyjet.com/Index/lists/catid/27/kid/19/p/4.html)

  (7)ADME and Toxicology - ADME及毒理学相关产品 

(http://www.amyjet.com/Index/lists/catid/27/kid/19/p/2.html)

  (8)3D Culture Products - 3D细胞培养相关产品 

(http://www.amyjet.com/Index/lists/catid/27/kid/19/p/1.html)


LONZA(龙沙):瑞士的制药化工巨头,龙沙集团是一家以生命科学为主导,在生物化学、精细化工、功能化学等行业均处于领先地位的全球性跨国公司,具有一百多年历史,总部位于瑞士巴塞尔,在欧洲、美洲、亚洲总共有35个研发和生产中心,其中LONZA的大部分生物技术产品在美国研发生产。LONZA(龙沙)主要生产生命科学产品以及多种类的精细和特殊化工产品,以高科技生物技术与优质产品闻名世界。


Lonza is one of the world’s leading and most-trusted suppliers to the pharmaceutical, biotech and specialty ingredients markets. As an integrated solutions provider, Lonza is boosting its value creation along and beyond the healthcare continuum with a strong focus on patient healthcare, consumer preventive healthcare and consumer's healthy environment. Lonza harnesses science and technology to create products that support safer and healthier living and that enhance the overall quality of life. With the recent Capsugel acquisition, Lonza now offers products and services from the custom development and manufacturing of active pharmaceutical ingredients to innovative dosage forms for the pharma and consumer health and nutrition industries.  



更多详情请联系 

艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com


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BioVision.jpg

BioVision公司是世界顶尖的细胞凋亡和信号传导产品生产商,产品包括检测试剂盒,抗体及重组蛋白,涵盖了细胞凋亡、细胞信号传导和细胞因子研究的各个方面。凋亡产品包括Annexin V 试剂盒、半胱天冬氨酸蛋白酶(Caspases)试剂盒及底物和抑制剂、线粒体膜电位试剂盒、梯状DNA 电泳和TUNEL 试剂盒、凋亡诱导剂、凋亡相关抗体和化学品、细胞增殖检测试剂盒等。

 

BioVision, Inc., is a privately held Life Science company headquartered in the beautiful San Francisco Bay Area. BioVision develops and offers a wide variety of products including assay kits, antibodies, recombinant proteins & enzymes, and other innovative research tools for studying Apoptosis, Metabolism, Cell Proliferation, Cellular Stress, Cell Damage and Repair, Diabetes, Obesity and Metabolic Syndrome, Stem Cell Biology, Gene Regulation, Signal Transduction, etc. BioVision's products are currently being sold in more than 60 countries worldwide.

 

BioVision公司的主要产品包括:

Antibodies & Supporting Tools

Biochemicals

Cytokines & Growth Factors

ELISA Kits

Enzyme Inhibitors

EZSolution™ Ready-to-Use Products

Fluorescent Proteins

Laboratory accessories

Metabolism Assay Kits

Molecular Biology

Protein A,G,L & Affinity Conjugates

Proteins & Enzymes

Protein Extraction & Purification

Signaling Pathways

按研究领域细分

Apoptosis

Autophagy

Cardiovascular

Cancer

Cell Damage & Oxidative Stress

Cell Proliferation, Viability & Cytotoxicity

Diabetes, Obesity & Metabolic Syndrome

Drug Metabolism & Disposition

Epigenetics

Exosomes

Infectious Diseases

Metabolism

Neuroscience

Proteostasis

Signal Transduction

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Affinity Biologicals.jpg


艾美捷科技有限公司代理Affinity Biologicals公司产品,如下:


(1)Matched-Pair Antibody Sets

http://www.amyjet.com/Index/lists/catid/27/kid/52/p/1.html

(2)Factor Inhibitor Plasmas

http://www.amyjet.com/Index/lists/catid/27/kid/52/p/2.html

(3)Control Plasma-Diagnostic

http://www.amyjet.com/Index/lists/catid/27/kid/52/p/2.html

(4)Deficient Plasmas

http://www.amyjet.com/Index/lists/catid/27/kid/52/p/3.html

(5)Complete ELISA Kit

http://www.amyjet.com/Index/lists/catid/27/kid/52/p/5.html

(6)Antibodies

http://www.amyjet.com/Index/lists/catid/27/kid/52/p/6.html


Affinity Biologicals公司成立于1987年,提供包括凝血相关抗体、ELISA试剂盒、无蛋白酶抑制剂血浆和校准血浆等系列产品。Affinity Biologicals还提供蛋白纯化、抗体生产、检测方法开发、定制生产等服务。

 

Affinity Biologicals, Inc. is a primary manufacturer of products used worldwide in thrombosis and hemostasis research and medical diagnostics. Our products include an extensive line of antibodies to coagulation and hemostasis related proteins, conjugates, antibody pairs for immunoassay of human and animal analytes, the VisuLize line of complete ELISA kits, and a full line of human plasma products including immune-depleted plasmas, calibrators and controls. Custom Services include protein purification, antibody production, assay development, custom manufacturing and lyophilization.

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艾美捷科技有限公司,代理LDN公司全系列ELISA试剂盒产品。


LDN公司是德国专业的免疫检测试剂生产厂家。LDN成立于1996年,已经成长为全球领先的生物胺免疫分析产品的公司,拥有超过35名员工。目前,LDN在60多个国家提供200多种产品。客户来自临床实验室、研究机构、制药公司和食品行业。

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主要产品和服务:

产品领域检测物产品名称货号规格
ResearchSerotonin
Serotonin Research ELISA
BA E-590096T
ResearchCatecholaminesAdrenaline Research ELISABA E-510096T
ResearchCatecholaminesNoradrenaline Research ELISABA E-520096T
ResearchCatecholaminesDopamine Research ELISABA E-530096T
ResearchCatecholamines2-CAT (A-N) Research ELISABA E-540096T
ResearchCatecholamines2-CAT (N-D) Research ELISABA E-550096T
ResearchCatecholamines3-CAT Research ELISABA E-560096T
ResearchHistamineHistamine Research ELISA TMBA E-580096T
ResearchTryptophanTryptophan ELISABA E-270096T
ResearchGABAGABA ELISABA E-250096T
ResearchGlycineGlycine ELISABA E-210096T
ResearchKynurenineKynurenine ELISABA E-220096T
ResearchCitrullineCitrulline ELISABA E-280096T
ResearchANIMAL RESEARCHTestosterone Rat/Mouse ELISAAR E-800096T
ResearchANIMAL RESEARCHCorticosterone Rat/Mouse ELISAAR E-810096T
ResearchANIMAL RESEARCHProlactin Rat ELISAAR E-820096T
ResearchANIMAL RESEARCHEstrone-3-Sulfate Equine ELISAAR E-830096T
ResearchANIMAL RESEARCHProlactin Canine ELISAAR E-840096T
ResearchANIMAL RESEARCHTSH Canine ELISAAR E-850096T
ResearchANIMAL RESEARCHTSH Rat ELISAAR E-860096T
ResearchANIMAL RESEARCHProgesterone Mouse/RatAR E-870096T
ResearchANIMAL RESEARCHEstradiol RatAR E-880096T
Food Safety
HistaSure™ ELISA High SensitiveFC E-310096T
Food Safety
HistaSure™ ELISA Fast Track (48 determinations)FC E-360096T
Food Safety
HistaSure™ XL ELISA Fast Track (480 determinations)FC E-390096T
Food Safety
HistaSure™ Fish Rapid TestFC L-320096T
EndocrinologyAndrogen AssessmentAndrostenedione ELISAAA E-100096T
EndocrinologyAndrogen AssessmentDHEA-S ELISAAA E-110096T
EndocrinologyAndrogen AssessmentSHBG ELISAAA E-120096T
EndocrinologyAndrogen AssessmentTestosterone ELISAAA E-130096T
EndocrinologyAndrogen AssessmentAndrostanediol-Glucuronide ELISAAA E-150096T
EndocrinologyAndrogen AssessmentDHEA ELISAAA E-160096T
EndocrinologyAndrogen AssessmentDHT ELISAAA E-170096T
EndocrinologyAndrogen AssessmentFree Testosterone ELISA 2nd GenerationAA E-180096T
EndocrinologyFertility & ReproductionEstradiol ELISAFR E-200096T
EndocrinologyFertility & ReproductionFree Estriol ELISAFR E-210096T
EndocrinologyFertility & ReproductionEstrone ELISAFR E-230096T
EndocrinologyFertility & ReproductionProgesterone ELISAFR E-250096T
EndocrinologyFertility & ReproductionPregnenolone ELISAFR E-270096T
EndocrinologyFertility & Reproduction17-OH-Progesterone ELISAFR E-280096T
EndocrinologyMetabolismC-Peptide ELISAME E-010096T
EndocrinologyMetabolismhGH ELISAME E-020096T
EndocrinologyMetabolismLeptin ELISAME E-030096T
EndocrinologyMetabolismIGFBP-1 ELISAME E-040096T
EndocrinologyMetabolismIGF-1 ELISAME E-050096T
EndocrinologyMetabolismInsulin ELISAME E-090096T
EndocrinologyMineral/Salt balanceCortisol ELISAMS E-500096T
EndocrinologyMineral/Salt balanceCortisol Urine ELISAMS E-510096T
EndocrinologyMineral/Salt balanceAldosterone ELISAMS E-520096T
EndocrinologyMineral/Salt balanceActive Renin ELISAMS E-530096T
EndocrinologyMineral/Salt balanceCorticosterone ELISAMS E-540096T
EndocrinologyMineral/Salt balancePlasma Renin Activity ELISA (PRA)MS E-560096T
EndocrinologyMineral/Salt balance25-OH-Vitamin D (total) ELISAMS E-580096T
EndocrinologyThyroid FunctionTSH ELISA 2nd GenerationTF E-200096T
EndocrinologyThyroid FunctionfT3 ELISA 2nd GenerationTF E-210096T
EndocrinologyThyroid FunctionfT4 ELISA 2nd GenerationTF E-220096T
EndocrinologyThyroid FunctionT3 ELISA 2nd GenerationTF E-230096T
EndocrinologyThyroid FunctionT4 ELISA 2nd GenerationTF E-240096T
EndocrinologyThyroid FunctionReverse T3 (rT3) ELISATF E-250096T
EndocrinologyTumor MarkersCEA ELISATM E-410096T
EndocrinologyTumor MarkersCA 125 ELISATM E-430096T
EndocrinologyTumor MarkersCA 15-3 ELISATM E-440096T
EndocrinologyTumor MarkersCA 19-9 ELISATM E-450096T
EndocrinologyTumor Markersβ2-Microglobulin ELISATM E-460096T
EndocrinologyTumor MarkershNSE ELISATM E-470096T
EndocrinologyTumor MarkersChromogranin A ELISATM E-900096T
EndocrinologyDisease MarkersCRPHigh Sensitive ELISADM E-460096T
EndocrinologySaliva AssaysCortisol Saliva ELISASA E-600096T
EndocrinologySaliva AssaysTestosterone Saliva ELISASA E-610096T
EndocrinologySaliva AssaysEstradiol Saliva ELISASA E-620096T
EndocrinologySaliva AssaysProgesterone Saliva ELISASA E-630096T
EndocrinologySaliva Assays17-OH-Progesterone Saliva ELISASA E-640096T
EndocrinologySaliva AssaysDHEA-S Saliva ELISASA E-650096T
EndocrinologySaliva AssaysFree Estriol Saliva ELISASA E-660096T
EndocrinologySaliva AssaysAndrostenedione Saliva ELISASA E-670096T
EndocrinologySaliva AssaysIgA Saliva ELISASA E-680096T
EndocrinologySaliva AssaysAlpha-Amylase Saliva ELISASA E-690096T
EndocrinologySaliva AssaysDHEA Saliva ELISASA E-700096T
EndocrinologySaliva AssaysEstrone Saliva ELISASA E-710096T
EndocrinologySaliva AssaysSALI – SETCATALOG96T
EndocrinologySaliva AssaysSALI – SET 100SA D-610096T
EndocrinologySaliva AssaysSALI – SET 500SA D-650096T
EndocrinologyAnimal ResearchTestosterone Rat/Mouse ELISAAR E-800096T
EndocrinologyAnimal ResearchCorticosterone Rat/Mouse ELISAAR E-810096T
EndocrinologyAnimal ResearchProlactin Rat ELISAAR E-820096T
EndocrinologyAnimal ResearchEstrone-3-Sulfate Equine ELISAAR E-830096T
EndocrinologyAnimal ResearchProlactin Canine ELISAAR E-840096T
EndocrinologyAnimal ResearchTSH Canine ELISAAR E-850096T
EndocrinologyAnimal ResearchTSH Rat ELISAAR E-860096T
EndocrinologyAnimal ResearchProgesterone Mouse/RatAR E-870096T
EndocrinologyAnimal ResearchEstradiol RatAR E-880096T
Glycine in urineGlycine in urineGlycine ELISABA E-210096T
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更多详情请联系 

艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com

< " data-original="http://aviva.51antibodies.com/template/company/xys_lvse/skin/image/lazyLoad.jpg" alt="LDN公司全系列ELISA Kits">
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GORYO Chemical.png

艾美捷科技有限公司,代理GORYO Chemical公司全系列探针产品。


GORYO Chemical公司位于日本札幌市,是一家生产荧光探针的专业化供应商。由于荧光探针的化学特性,使得研究者可以利用它对细胞内运行机理进行可视化研究。GORYO Chemical与东京大学和北海道大学合作,在荧光试剂领域领已取得领先的地位。目前,GORYO Chemical在日本已经开始针对癌症检测推出临床使用的探针,在未来,这将为指导治疗提供新的方法。

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主要产品和服务:

AcidiFluor™ SeriesFluorescent probes to detect acidic pHSize
GC301AcidiFluor™ ORANGE10 μg × 20
GC3011AcidiFluor™ ORANGE10 μg × 10
GC302AcidiFluor™ ORANGE-NHS1 mg
GC303AcidiFluor™ ORANGE-NHS5 μg × 5
GC304AcidiFluor™ ORANGE Labeling Kit5 times labeling
GC305AcidiFluor™ ORANGE-Zymosan A1 mg
GC306AcidiFluor™ ORANGE-Dextran 10k1 mg
GC309AcidiFluor™ ORANGE-Transferrin1 mg
GC310-01HaloTag® AcidiFluor™ ORANGE Ligand30 nmol
GC310-02HaloTag® AcidiFluor™ ORANGE Ligand60 nmol
CalxFluor™ SeriesFluorescent probes to detect calcium ionsSize
GC405CaSiR-1 potassium salt500 µg
GC503CaTM-2 AM500 μg
GC504CaTM-2 AM50 μg × 10
GC5041CaTM-2 AM50 μg × 5
GC507CaTM-3 AM40 nmol × 5
GlycoFluor™ SeriesFluorescent probes to detect glycosidase activitySize
GC601GlycoYELLOW™ –βGal50 μg × 10
GC611GlycoGREEN™-βGal30 nmol × 5
SK4001-01TokyoGreen®–βGal1 mg
SK4002-01TokyoGreen®–βGlu1 mg
SK4003-01TokyoGreen®–βGlcU(Na)1 mg
HaloFluor™ SeriesFluorescent probes combined with Halotag® ligandSize
GC310-01HaloTag® AcidiFluor™ ORANGE Ligand30 nmol
GC310-02HaloTag® AcidiFluor™ ORANGE Ligand60 nmol
A201-01HaloTag® SaraFluor™ 650B ligand15 nmol
A201-02HaloTag ®SaraFluor™ 650B ligand15 nmol × 2
ProteoFluor™ SeriesFluorescent probes to detect protease activity in cancer cellSize
GC801ProteoGREEN™-gGlu20 μg × 10
GC811EP-HMRG30 nmol x 5
StemFluor™ SeriesFluorescent probes to detect human iPS/ES cellsSize
GC7001-01Kyoto Probe 1 (KP-1)10 μg × 5
GC7001-02Kyoto Probe 1 (KP-1)10 μg × 10
SaraFluor™ SeriesFluorescent probes for labeling/imagingSize
ST1003-10SaraFluor™ 488-NHS5 nmol x 5
ST1003-11SaraFluor™ 488-NHS1 mg
ST1003-15SaraFluor™ 488-NHS1 mg x 5
ST1003-21SaraFluor™ 488-maleimide1 mg
ST1003-25SaraFluor™ 488-maleimide1 mg x 5
ST1003-31SaraFluor™ 488-COOH1 mg
ST1003-35SaraFluor™ 488-COOH1 mg x 5
ST1003-41SaraFluor™ 488-NH21 mg
ST1003-45SaraFluor™ 488-NH21 mg x 5
ST1006-10SaraFluor™ 600-NHS5 nmol x 5
ST1006-11SaraFluor™ 600-NHS1 mg
ST1006-15SaraFluor™ 600-NHS1 mg x 5
ST1006-21SaraFluor™ 600-maleimide1 mg
ST1006-25SaraFluor™ 600-maleimide1 mg x 5
ST1006-31SaraFluor™ 600-COOH1 mg
ST1006-35SaraFluor™ 600-COOH1 mg x 5
ST1006-41SaraFluor™ 600-NH21 mg
ST1006-45SaraFluor™ 600-NH21 mg x 5
ST1008-10SaraFluor™ 650-NHS5 nmol x 5
ST1008-11SaraFluor™ 650-NHS1 mg
ST1008-15SaraFluor™ 650-NHS1 mg x 5
ST1008-21SaraFluor™ 650-maleimide1 mg
ST1008-25SaraFluor™ 650-maleimide1 mg x 5
ST1008-31SaraFluor™ 650-COOH1 mg
ST1008-35SaraFluor™ 650-COOH1 mg x 5
ST1008-41SaraFluor™ 650-NH21 mg
ST1008-45SaraFluor™ 650-NH21 mg x 5
ST1010-10SaraFluor™ 700-NHS5 nmol x 5
ST1010-11SaraFluor™ 700-NHS1 mg
ST1010-15SaraFluor™ 700-NHS1 mg x 5
ST1010-21SaraFluor™ 700-maleimide1 mg
ST1010-25SaraFluor™ 700-maleimide1 mg x 5
ST1010-31SaraFluor™ 700-COOH1 mg
ST1010-35SaraFluor™ 700-COOH1 mg x 5
ST1010-41SaraFluor™ 700-NH21 mg
ST1010-45SaraFluor™ 700-NH21 mg x 5
ST1011-10SaraFluor™ 720-NHS5 nmol x 5
ST1011-11SaraFluor™ 720-NHS1 mg
ST1011-15SaraFluor™ 720-NHS1 mg x 5
ST1011-21SaraFluor™ 720-maleimide1 mg
ST1011-25SaraFluor™ 720-maleimide1 mg x 5
ST1011-31SaraFluor™ 720-COOH1 mg
ST1011-35SaraFluor™ 720-COOH1 mg x 5
ST1011-41SaraFluor™ 720-NH21 mg
ST1011-45SaraFluor™ 720-NH21 mg x 5
A201-01HaloTag® SaraFluor™ 650B ligand15 nmol
A201-02HaloTag ®SaraFluor™ 650B ligand15 nmol × 2
A202-01SaraFluor™ 650B goat anti-mouse IgG100 μg
A203-01SaraFluor™ 650B goat anti-rat IgG100 μg
A204-01SaraFluor™ 650B goat anti-rabbit IgG100 μg
A208-01SaraFluor™ 650B-NHS100 μg
A209-01SaraFluor™ 650B-maleimide100 μg
A218-01SaraFluor™ 488B-NHS100 μg
MetalloFluor™ SeriesFluorescent probes to detect metall ionSize
GC901FeRhoNox™-150 μg × 10
GC902CopperGREEN™50 nmol × 5
GC903-01FerroFarRed™50 nmol × 5
GC904-01FerroOrange35 nmol × 5
GC904-02FerroOrange35 nmol × 1
SK2001-01ZnAF®-21 mg
SK2002-01ZnAF®-2 DA1 mg
NOFluor™ SeriesFluorescent probes to detect niric oxideSize
SK1001-01DAF-21 mg
SK1002-01DAF-2 DA1 mg
SK1003-01DAF-FM1 mg
SK1004-01DAF-FM DA1 mg
SK1005-01DAR-4M1 mg
SK1006-01DAR-4M AM1 mg
HypoFluor™ SeriesFluorescence probes for hypoxia detectionSize
A101-01MAR25 μg × 5
ROSFluor™ SeriesFluorescent probes to detect reactive oxigen speciesSize
SK3001-02Hydroxyphenyl Fluorescein (HPF)1 mg
SK3002-02Aminophenyl Fluorescein (APF)1 mg
SK3003-01NiSPY-31 mg
GC3004-01OxiORANGE™100 nmol ×5
GC3006-01HySOx20 μg × 5
GC3007-01HYDROP30 nmol × 3
GC3008-01HYDROP-EX30 nmol × 3
FRETFluor™ SeriesFRET based fluorescent probesSize
A401-1QuicGSH3.025 nmol × 5
A401-2QuicGSH3.025 nmol × 2
A402-1SSip-1 DA60 nmol × 3
NIRFluor™ seriesNear infrared fluorescent probes
A501-01ICG-NHS ester1 mg
A501-05ICG-NHS ester1 mg × 5
A501-10ICG-NHS ester1 mg × 10
A502-01ICG-maleimide1 mg
A502-05ICG-maleimide1 mg × 5
A502-10ICG-maleimide1 mg × 10
Bioluminescent seriesFluorescent probes for in vivo imagingSize
RS101-01D-Luciferin potassium salt1 g
POLARIC™ SeriesFluorescent probes for staining cell membrane and bacteriaSize
GC101POLARIC™-500c6F1 μg × 10
GC1011POLARIC™-500c6F1 μg × 5
GC102POLARIC™-500BCS5 μg × 10
GC1021POLARIC™-500BCS5 μg × 5
GC2021POLARIC™-NHS1 mg
GC2031POLARIC™-maleimide1 mg
GC211POLARIC™ Labeling Kit5 times labelng


<

更多详情请联系 

艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com

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艾乐美生物科技有限公司(AllerMAbs Co., Ltd.)成立于2015年,是台湾一家专注于生产高亲和力、高纯度并具有过敏原特异性的嵌合人类IgE单克隆抗体的生物公司。公司创办人团队在科研过程中发现市面上缺乏多样的IgE单克隆抗体,特別是具有过敏原特异性的人IgE 单抗。如果能制备出这种抗体,将有助于IgE 相关领域的研究工作。因此,AllerMAbs公司团队开始思考与研究利用基因克隆动物来制造人类 IgE 抗体的可行性,经过数年的努力于 2014年开发出人类IgE 抗体基因嵌入小鼠,通过杂交瘤技术 (Hybridoma technology),成功地研制出分泌嵌合人类IgE 单抗的 IgE 杂交瘤与纯化 IgE 抗体。经测试,此种嵌合人类IgE 单抗的物化性质与对免疫细胞的活性,皆与人类IgE 抗体一致,研究成果于2015 年发表在国际学术期刊上。

 

AllerMAbs的产品解决了目前人类IgE抗体不易制备的问题,让嵌合人类IgE抗体可以成为人类IgE抗体的替代品,并提供一个更稳定、更符合血清IgE检测系统的校正品,让临床血清IgE的检测结果更加准确与可靠。

 

其利用动物基因转殖技术,将组成人类IgE抗体分子的ε重链(Heavy chain)和κ轻链(Light chain)的编码基因(Encoding genes),分別嵌入(Knock-in)小鼠胚胎干细胞(Embryonic stem cells, ES cells)的γ1重链和κ轻链基因的位置,接着把胚胎干细胞分別植入孕母鼠体内,并将其带有嵌入基因之成鼠交互配种,最后得到带有人类IgE抗体重链和轻链基因的基因嵌入小鼠(HεκKI mice),且体内能制造完整的嵌合人类IgE抗体分子。

 

技术优势

容易制备IgE杂交瘤与IgE单抗

过敏原特异性

良好的亲和力与专一性

高纯度与高稳定性

可结合至嗜碱性粒细胞上的IgE受体与刺激細胞

可大量生产与高浓度制备

非人类血液来源(相较于血清IgE抗体)

适合用作检测用的校正品

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